Unveiling The Innovative Applications of Nano-binary Oxide ZnO/SiO2 Antibiotics Medical Ointment Apply on Wound Dressings
نویسندگان
1 Department of Chemistry, University of Babylon, College of Science, Iraq
2 Department of Chemistry, University of Babylon, College of Science, Iraq
3 Department of Microbiology, Hammurabi College of Medicine, University of Babylon, Iraq
doi
10.22052/JNS.2026.01.005چکیده
Current research in this field aims to tackle the issue of antibiotic resistance by focusing on the role of pure nanocomposites in health applications. in an eco-friendly manner, depending on the solution gel route used to prepare nano binary oxide ZnO/SiO₂. The characterization of the nano-binary oxide ZnO/SiO2 included), x-ray diffraction (XRD), Brunauer-Emmett-Teller surface area design (BET), Energy Dispersive X-ray (EDX), Field Emission Electron Microscopy (FE SEM, and microplate reader (ELISA). Results show higher activity of the value 500µg/ml nano binary oxide ZnO/SiO2 against Gram-negative microorganism Escherichia Coli (E. Coli). With a large surface area and pore circulation, the nano binary oxide ZnO/SiO₂ exhibits high activity. In this research, a nano-medical ointment was developed using a ZnO/SiO2 composite with an average particle size 14 -50 nm to enhance the antibacterial efficacy and accelerate the healing of wounds and burns. Results from the medical ointment against Gram-negative bacteria (E. Coli) were promising, with reduced toxicity of ZnO/SiO₂ nanoparticle ointment, offering an innovative solution as a broad-spectrum topical antibiotic, with accelerated tissue healing and excellent safety.