فهرست نشریات علمی دسترسی آزاد ایران

In recent years, nanocarriers composed of polymers, liposomes, and other materials have gained attention for the delivery of nucleotides and therapeutic drugs. This study investigates the use of graphene oxide (GO) as a key component in nanocarriers, owing to its unique chemical structure, high surface area, biocompatibility, and versatile functional properties. GO exhibits strong potential for applications in drug and gene delivery, tissue engineering, and other biomedical fields due to its ability to interact effectively with various compounds. In this work, a novel GO–MgO–chitosan nanocarrier was synthesized and evaluated for drug loading and release capabilities. Comprehensive characterization techniques—including Fourier-transform infrared spectroscopy (FT-IR), scanning electron microscopy (SEM), X-ray diffraction (XRD), Raman spectroscopy, thermogravimetric analysis (TGA), and zeta potential analysis—were conducted before and after drug incorporation. These analyses confirmed the successful fabrication of the nanocarrier and provided insight into structural, morphological, and thermal changes associated with drug loading, supporting its potential in targeted drug delivery systems.