Green Synthesis of Triangular Silver Nanoparticles Using Garden Cress Seed Extract Based on Gallic Acid and Their Antifungal Activity

نویسندگان

1 Department of Chemistry, College of Science, University of Babylon, Babylon, Iraq

2 Department of Chemistry, College of Science, University of Babylon, Babylon, Iraq

3 Department of Chemistry, College of Science, University of Babylon, Babylon, Iraq

doi
10.22052/JNS.2026.01.043
چکیده

Nanotechnology is a developing discipline in pharmaceutical sciences, characterized by particles that exist at the nanoscale and have enhanced reactivity compared to their larger counterparts. This work discusses a green production technique to prepare triangle silver nanoparticles (AgTNPs) using garden cress seed extract. Whole garden cress seed, commonly referred to as Rashaad seeds in the Middle East and Arabic countries, were extracted using distilled water to obtain the essential extract. The chemical components of the aqueous extract were analyzed using Electron Ionization Gas Chromatography-Mass Spectrometry (EI-GC/MS).  Subsequently, the extract was employed as a reducing agent for the synthesis of AgTNPs.  After the synthesis and purification of nanoparticles, UV-Vis Spectroscopy, Fourier Transform Infrared (FTIR) spectroscopy, X-ray Diffraction (XRD), Energy Dispersive X-ray (EDX) analysis, and Scanning Electron Microscopy (SEM) were employed for comprehensive characterization. Additionally, Gallic Acid was then loaded on these nanoparticles, and their antifungal activities were investigated before and after modification. The results showed significant inhibition when (AgTNPs) were tested in comparison with plant extract, while they showed remarkable activity as antifungal when Gallic Acid was loaded compared to free (AgTNPs). This work presents the novel use of plant extract for preparing triangular silver nanoparticles .