A FORC-Assisted Magnetic Hyperthermia Investigation of Fe3O4 Nanoparticles Synthesized at Different pH Values
نویسندگان
1 Department of Chemistry College of Science, University of Basrah, Iraq
2 Department of Marine Chemistry, Marine Science Center, University of Basrah, Iraq
3 Department of Physics, College of Science, University of Basrah, Iraq
4 Department of Pharmaceutical Chemistry, College of Pharmacy, University of Basrah, Iraq
doi
10.22052/JNS.2025.04.036چکیده
Exploiting characteristics of magnetic nanoparticles (MNPs), especially superparamagnetic (SP) behavior, can lead to advancements in their possible practical applications such as hyperthermia therapy. Here, a facile co-precipitation method with different pH values is employed to synthesize Fe3O4 MNPs, followed by thoroughly characterizing them in terms of structural, morphological, magnetic, and calorimetric properties. According to X-ray and first-order reversal curve (FORC) analyses, all of the spinel Fe3O4 MNPs are found to show SP features. Hyperthermia measurements of ferrofluids acting as nanoheaters at a concentration of 8 mg/ml in a distilled water medium are carried out at a frequency of 400 kHz under different alternating magnetic field intensities. The maximum specific loss power (SLP) value and SP fraction are obtained to be 99 W/g and 50% using pH=12, respectively, resulting from a low hydrodynamic size distribution, high SP fraction and saturation magnetization, along with a considerably low coercive field of the MNPs.
