Green Preparation, Optimization and Antibacterial Activity of Hydroxyapatite Nanoparticles by Using Senna Italica Leaf Extract Against Pathogenic Bacteria Isolated from Postoperative Endophthalmitis
نویسندگان
1 Department of Biology, College of Science, Mustansiriyah University, Baghdad, Iraq
2 Department of Biology, College of Science, Mustansiriyah University, Baghdad, Iraq
3 Department of Physics, College of Science, Mustansiriyah University. Baghdad, Iraq
doi
10.22052/JNS.2025.04.053چکیده
The need to find new antimicrobial compounds and standard testing procedures to control transmissible diseases has increased highly as antibiotic resistance has increased. The Minimum Inhibitory Concentration (MIC) Assay of HAp-NPs nanoparticles was used to measure their antibacterial activity. Without the use of any equipment, MIC can be visually assessed. HAp-NPs nanoparticles exhibited significant antibacterial activity against the isolation of Pseudomonas aeruginosa, Enterobacter cloacae, and Staphylococcus aureus from postoperative endophthalmitis. These bacteria were selected due to their high level of antibiotic resistance and repeatability. An extract from Senna italica leaves was used to create the hydroxyapatite nanoparticles (HAp-NPs) used in this study. The purpose of this study was to investigate the antibacterial properties of environmentally friendly hydroxyapatite nanoparticles (HAp-NPs) against harmful bacteria. Fourier-transform infrared spectroscopy (FTIR), a Field Emission Scanning Electron Microscope (FE-SEM), energy-dispersive X-ray spectroscopy (EDX), and X-ray diffraction analysis (XRD) were used to characterize the synthesized hydroxyapatite powder.
