فهرست نشریات علمی دسترسی آزاد ایران

This research investigated the synthesis and applications of various functionalized graphene oxide (GO) derivatives with amine groups. Graphene oxide was synthesized using the Hummers’ method, yielding a black powder with a 68% yield. Its properties were studied using FT-IR spectroscopy, 1H-NMR, FESEM, and XRD analysis, showing consistency with previous literature. Subsequently, several GO derivatives were prepared by incorporating amine compounds, such as 3-aminophenol (GO-1), 4-aminouracil (GO-2), 2-aminobenzoic acid (GO-3), naphthylamine (GO-4), and o-anisidine (GO-5). Spectroscopic and XRD analyses of these derivatives revealed changes in structural and compositional properties, indicating successful functionalization. The antimicrobial and antioxidant activities of the functionalized GO derivatives were evaluated. Antibacterial activity tests showed that GO-1 was the most effective against Staphylococcus aureus, Bacillus subtilis, and Escherichia coli, surpassing conventional antibiotics such as ampicillin. For antifungal activity, comparative data with fluconazole were not available, but previous studies suggest that functionalized graphene oxide may possess antifungal properties. In the antioxidant activity test using the DPPH assay, the derivatives displayed significant variations in their ability to scavenge free radicals. Among these derivatives, GO-1 demonstrated the highest antioxidant activity with a scavenging rate of up to 56.3% at a concentration of 75 µg/mL, and an IC50 value of 25.4 µg/mL. These results support the effectiveness of functional modifications on graphene oxide in enhancing its antioxidant properties. Amine-modified graphene oxide has improved properties in anti-oxidant and anti-microbial applications, that is interesting for environment and medical applications.