فهرست نشریات علمی دسترسی آزاد ایران

The purpose of this study is to determine the antibacterial effects of different concentrations of zinc oxide (ZnO) nanoparticles and extract from Capsicum annuum L. (pepper fruit) on Staphylococcus mutans (S. mutans) and Staphylococcus aureus (S. aureus) isolates that were obtained from dental caries. ZnO nanoparticles were achieved with a size range of 10–30 nm and a purity level of 99.8 %, and pepper fruit extracts were made using the Soxhlet extraction method. Several different concentrations were used in the agar well diffusion method to evaluate the effectiveness of antibacterial agents. According to the findings, ZnO nanoparticles exhibited inhibitory zones ranging from 2.11 to 2.97 mm for S. mutans and 2.01 to 2.66 mm for S. aureus, with 1.0 mg/mL for the maximum activity. The antibacterial activity of products increased with increasing concentration of the extract, reaching its maximum inhibition at 300 mg/mL. The combination of ZnO nanoparticles and extract from Capsicum annuum demonstrated dose-dependent antibacterial activity, indicating that these substances can be used in therapeutic applications against oral infections.