Pulse Laser Ablation Synthesis of Chitosan-ZnO-TiO2 Nanocomposites for Bacterial Inhibition
نویسندگان
1 Department of Basic Science, Faculty of Density, University of Babylon, Babylon, Iraq
doi
10.22052/JNS.2025.02.014چکیده
This study investigated the antimicrobial properties of chitosan-based nanocomposites against E. coli and Porphyromonas bacteria. The nanocomposites, including CS, CS-ZnO, CS-TiO2, and CS-ZnO-TiO2, were synthesized using pulsed laser ablation in liquid (PLAL). Characterization techniques confirmed the formation of nanoparticles with varying sizes and distributions.Antimicrobial assays demonstrated that the CS-ZnO-TiO2 nanocomposite exhibited superior inhibitory activity against both bacterial strains compared to the individual components or their binary combinations. The inhibition percentage increased with the concentration of the nanomaterials, highlighting the dose-dependent antibacterial effect. Statistical analysis confirmed significant differences in the antibacterial activity of the different nanomaterials.This study investigated the antimicrobial properties of chitosan-based nanocomposites against E. coli and Porphyromonas bacteria. The nanocomposites, including CS, CS-ZnO, CS-TiO2, and CS-ZnO-TiO2, were synthesized using pulsed laser ablation in liquid (PLAL). Characterization techniques confirmed the formation of nanoparticles with varying sizes and distributions. Antimicrobial assays demonstrated that the CS-ZnO-TiO2 nanocomposite exhibited superior inhibitory activity against both bacterial strains compared to the individual components or their binary combinations. The inhibition percentage increased with the concentration of the nanomaterials, highlighting the dose-dependent antibacterial effect. Statistical analysis confirmed significant differences in the antibacterial activity of the different nanomaterials. These findings suggest that the CS-ZnO-TiO2 nanocomposite has potential as a broad-spectrum antimicrobial agent, warranting further investigation into its mechanism of action and optimization for various applications.