فهرست نشریات علمی دسترسی آزاد ایران

Nanoparticles (NPs) display unique characteristics in contrast to conventional physio-chemical synthesis methods, they are utilized in a diverse array of life science fields. Metal nanoparticles synthesized using green methods, primarily derived from plants and herbs, have attracted significant interest because of their inherent properties such as environmental friendliness, quick production, and cost efficiency. In this study, zinc oxide nanoparticles (ZnO-NPs) were synthesized through an aqueous extraction of Achillea fragrantissima, which served as a reducing agent. Following synthesis, the ZnO-NPs were characterized using a combination of techniques: ultraviolet-visible spectroscopy (UV-Vis), Fourier transform infrared (FTIR) spectroscopy, scanning electron microscopy (SEM), and energy-dispersive X-ray spectroscopy (EDX). The antioxidant potential of these synthesized ZnO-NPs was assessed using the DPPH assay, with varying concentrations of ZnO-NPs employed. The results demonstrated significant scavenging activity, with an IC50 value of 1.09 ± 0.09 mg/ml-1. Furthermore, the disk diffusion method was employed to assess the anti-bacterial efficacy of ZnO-NPs synthesized using green techniques against two pathogenic bacterial strains. The findings revealed that Staphylococcus aureus exhibited the highest susceptibility to the biosynthesized zinc oxide nanoparticles (ZnO-NPs), in contrast, Escherichia coli demonstrated the lowest sensitivity among the tested microorganisms. Overall, this research offers biologically synthesized ZnO-NPs as a viable substitute for artificial compounds, showcasing their potential applications as antioxidants and antibacterial agents within the biomedical and pharmaceutical sectors.