Characterization and Antimicrobial Activity of Hydrogel SA-g-P(AAc-co-Am) Leaded with Zinc Oxide Nanoparticles
نویسندگان
1 Department of Chemistry, College of Sciences for Women, Babylon University, Hilla, Iraq
2 Department of Chemistry, College of Education, University of Al-Qadisiyah, Al-Qadisiyah, Iraq
3 Department of Chemistry, College of Education, University of Al-Qadisiyah, Al-Qadisiyah, Iraq
4 Department of Chemistry, College of Education, University of Al-Qadisiyah, Al-Qadisiyah, Iraq
doi
10.22052/JNS.2024.04.011چکیده
The study focused on the characterization and biological activity of odium alginate graft poly (acrylic acid-co-acrylamide) Hydrogel (SA-g-P(AAc-co-Am)) impregnated with Zinc Oxide nanoparticles. Using FTIR, FE-SEM, TEM, and XRD techniques, various features were analyzed including the structural composition, surface morphology, and particle size. FTIR analysis showed active groups’ displacement after adsorption of ZnO nanoparticles, while FE-SEM unveiled a porous structure useful for adsorption. TEM images suggested uniform ZnO nanoparticles distribution, while XRD revealed an amorphous nature of the hydrogel. The biological activity against Staphyococcus aureus, Escherichia coli, and Aspergillums Niger was studied, with higher inhibition observed in the latter as the concentration of ZnO nanoparticles increased. However, differences in biological response were noticed, attributed to the varying nature of each organism.
