فهرست نشریات علمی دسترسی آزاد ایران

Chitosan is a non-toxic, high molecular weight, biodegradable polymer that closely resembles cellulose, a plant fiber. The main difference between chitosan and cellulose is the presence of an amine group (-NH2) in chitosan, as opposed to the hydroxyl group (-OH) found in cellulose. The aim of the study is the effect of nanochitosan production in Iran and Iraq on bacteria. Chitosan is derived from chitin, a substance found abundantly in the shells of shellfish such as crabs, lobsters, and shrimp. Extracting chitin from natural sources involves a process of demineralization and deproteinization. The purified chitin is then treated with concentrated alkaline compounds, such as sodium hydroxide, in a process known as deacetylation, resulting in chitosan. Chitosan exhibits enhanced antimicrobial properties when formed into nanoparticles and used as a coating material. Chitosan nanoparticles. These chitosan nanoparticle derivatives were evaluated for their antibacterial activity against Escherichia coli using methods such as well diffusion and microtiter method. The results showed the highest inhibition zone against Escherichia coli, the characteristics of nanochitosan, including its charge and size, ranged from 20-100 nm. The particle size of the nanochitosan was measured by (TEM) analyze the physical properties and morphology of nanochitosan. Microbiological investigations: Microbiological investigations were carried out to evaluate the antimicrobial properties of nanochitosan. Determination of MIC of nanochitosan was determined for some pathogenic bacteria, providing insights into their efficacy as antimicrobial agents. The results showed that among the nanostructures studied, the nanochitosan made from seashells from Iraq and Iran was the most effective. The results showed that the nanochitosan that appeared under the electron microscope and was characterized by its spherical shape had more antimicrobial properties compared to the nanochitosan that was characterized by its tubular shape due to its small size and its ability to penetrate bacterial cells easily.