Tandem Preparation of Furo[3,2-c]Coumarin Derivations Using Nano-Sized Fe3O4/N-GQDs Composite as a Magnetic Nanocatalyst
نویسندگان
1 Department of Chemistry, Bandar Abbas Branch, Islamic Azad University, Bandar Abbas, Iran
doi
10.22052/JNS.2024.04.026چکیده
Nitrogen-doped graphene quantum dots (N-GQDs), which are less than 10 nm in size, are an interesting member of carbon nanomaterials. N-GQDs nanostructures have been broadly used in several fields such as drug-gene delivery systems, photocatalytic reactions, and catalysts owing to their unique properties. However, N-GQDs have rarely been introduced as a catalyst in organic synthesis. Herein, Fe3O4 nanoparticles are prepared via the co-precipitation method. Due to further active sites on the surface of nanocomposites, nano-sized Fe3O4/N-GQDs composite can affect the catalytic activities. Also, the new nano-sized Fe3O4/N-GQDs magnetic composite has been well prepared by a green, low-cost, and easy co-precipitation route. The developing concern for sustainability in the chemical industry has led to the growth of “green chemistry”, which aims to limit the use of hazardous substances. One-pot multicomponent reactions (MCRs) are one of the powerful approaches to preparing a wide range of organic compounds. This protocol’s advantages in organic compound preparation include atom economy, good to excellent yields (up to 90%), short reaction time (28 min), a wide range of various products, and high catalytic activities. In this research, furo[3,2-c]coumarin derivations were prepared via microwave conditions using Fe3O4/N-GQDs composite as a nanocatalyst.