Nano Silica Phosphoric Acid: An Efficient Catalyst for the One- Pot Synthesis of 1, 2, 4, 5-Tetrasubstituted Imidazoles
نویسندگان
1 Department of Chemistry, College of Science, Yazd University, I. R. Iran .
2 Deprtment of Organic Chemistry, Faculty of Chemistry, University of Kashan, Kashan, I. R. Iran.
3 Deprtment of Organic Chemistry, Faculty of Chemistry, University of Kashan, Kashan, I. R. Iran.
doi
10.7508/jns.2012.01.012چکیده
Two simple protocols for the synthesis of 1, 2, 4, 5- tetrasubstitutedimidazoles using nano-SPA as a reusable, eco- friendly, inexpensive, and efficient catalyst are reported. Short reaction times, high yields, scale-up and easy workup are the advantages of these protocols.
