فهرست نشریات علمی دسترسی آزاد ایران

In the present study, the effects of the acute and chronic oral administrations (po) of curcumin in the absence and presence of morphine and naloxone was investigated on the sensation of acute corneal pain in rats. Acute corneal pain was induced by the local application of hypertonic saline (5 M NaCl) on the corneal surface, and the number of eye wipes was then counted for 30 s. Subcutaneous (sc) injections of morphine (1, 2 and 4 mg/kg) significantly suppressed corneal pain (p