فهرست نشریات علمی دسترسی آزاد ایران

Background and Objectives: Hospitalized children are particularly vulnerable to medical errors, which can have profound long-term effects on their health and development. Adverse events resulting from these errors contribute to significant morbidity and mortality in pediatric patients. Effective interventions to minimize errors are critical in improving patient safety. This systematic review aims to evaluate the effectiveness of interventions designed to reduce adverse events in pediatric hospital departments.    Methods: Following PRISMA 2020 guidelines, we searched Embase, PubMed, Google Scholar, Scopus, Cochrane Library, and Web of Science for studies published up to September 3, 2024. The search strategy was based on key terms including pediatric adverse events, medical errors, medicinal errors and medication error. We included randomized controlled trials, quasi-experimental studies, and before-and-after studies assessing interventions to reduce adverse events in pediatric departments. The primary outcome was the reduction of medicinal and non-medicinal errors. Risk of bias was assessed using the Cochrane Risk of Bias tool.    Results: A total of 23 studies, covering 22,871 participants from multiple countries, were included. Most studies (n = 19) focused on reducing medicinal errors, while four addressed non-medicinal errors. Interventions such as pharmacist-led strategies, technology-based solutions, educational programs, labelling tools, pictogram-based interventions, checklists, and multifaceted approaches were generally effective. Nineteen studies reported a significant reduction in error rates, while four found no significant impact.    Conclusion: Although various interventions effectively reduced pediatric medical errors, some studies demonstrated limited effectiveness. Factors such as small sample sizes, risk of bias, and observational designs affect the generalizability of findings.