فهرست نشریات علمی دسترسی آزاد ایران

Background and Objectives: Acute mesenteric venous thrombosis (AMVT) has complex etiological factors and is difficult to diagnose early, with complications such as intestinal necrosis severely impacting patient survival and prognosis. This study aims to explore the relationship between inflammation and coagulation-related blood indicators and intestinal necrosis in AMVT patients by analyzing these indicators, providing a reference for early identification of intestinal necrosis.    Methods: A retrospective review of clinical data from 110 AMVT patients between June 2022 and December 2023 was conducted. The patients were categorized into two groups: intestinal necrosis and non-intestinal necrosis. The general information, clinical manifestations, and laboratory examination results were compared. Furthermore, binary logistic regression was used to identify predictive factors for intestinal necrosis, with the predictive accuracy being assessed using ROC curves.   Results: Among the 110 AMVT patients, 38 had intestinal necrosis and 72 had non-intestinal necrosis. There were no notable disparities in gender, age, or other fundamental characteristics between the two groups (P<0.05). Nevertheless, notable variations were observed in laboratory examination indicators (white blood cell count (WBC), platelet-to-lymphocyte ratio (PLR), mean platelet volume (MPV), D-dimer (D-D)) (P>0.05). WBC, PLR, MPV and D-D were important factors for predicting intestinal necrosis. The AUC of combined application was 0.977, and the predictive sensitivity and specificity were 97.37% and 90.28%, respectively.    Conclusion: The joint application of WBC, PLR, MPV and D-D can more accurately predict the occurrence of intestinal necrosis in AMVT patients.