Exploring the Relationship between Blood Groups and Cancer: A Bibliometric and Machine Learning Analysis
نویسندگان
1 Department of Hematology and Medical Laboratory Sciences, Faculty of Allied Medicine, Kerman University of Medical Sciences, Kerman, Iran
2 Department of Medical Laboratory Sciences, School of Allied Medical Sciences, Arak University of Medical Sciences, Arak, Iran
3 Neurology Research Center, Kerman University of Medical Sciences, Kerman, Iran
4 Department of Internal Medicine, Hematology and Oncology Division, Kerman University of Medical Sciences, Kerman, Iran
5 HIV/STI Surveillance Research Center, and WHO Collaborating Center for HIV Surveillance, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, Iran
6 Cellular and Molecular Research Center, Gerash University of Medical Sciences, Gerash, Iran
doi
10.22034/ircmj.2025.492885.1688چکیده
Background and Objectives: The objective of this research is to establish a scientific map, conduct a structural analysis, and investigate the subject's evolution in order to identify emerging trends in articles concerning the correlation between blood groups and cancer. Methods: The Web of Science, Scopus, and PubMed databases were used to gather all publications from June 2003 to December 2023 that discussed the relationship between blood types and cancer. The R-package Biblioshiny was utilized to do bibliometric analysis. Results: A total of 2,951 papers were examined and evaluated. Since 2013, the number of publications related to blood groups and cancer has decreased. The most influential journals are Transfusion, Plos One, and Bone Marrow Transplantation. The United States, China, and Japan lead the field, with the US National Cancer Institute making significant contributions. The word cloud reveals frequent discussion topics such as ABO blood group, kidney transplant, gastric cancer. The theme evolution map from 2003 to 2015 shows significant discussion on transfusion, transplantation, Helicobacter pylori, bone marrow, and liver transplantation. From 2016 to 2023, the prevailing subjects include liver transplantation, ABO blood group, Helicobacter pylori, ovarian cancer, and chemokines. Conclusion: The scientometric analysis revealed a changing trend in research output, showing a notable increase until 2013, followed by a decline. The thematic analysis indicates a shift in research focus over time, moving from topics like transfusion, transplantation, and Helicobacter pylori to liver transplantation, the ABO blood group system, ovarian epithelial cancer, and chemokines.
