فهرست نشریات علمی دسترسی آزاد ایران

Background and Objectives: Severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) responsible for the COVID-19 outbreak, is an RNA virus of the genus Beta-Coronavirus. This study aimed to investigate the relationship between blood group antigens and susceptibility to infection, clinical manifestations, and prognosis of patients with COVID-19 identified in the city of Sanandaj.   Methods: In this study 420 COVID-19 patients (confirmed with PCR testing) in Sanandaj (Iran) took part in the study in 2020. The demographic, symptoms, hospitalization status, comorbidity, mortality rate of the patients were registered based on their medical records. Blood type of the patients were also determined testing their blood samples. The data were then analyzed using STATA 16 software.   Results: The findings showed that the mean age of the participants was 58.7±18.32 years. The O blood group distribution was significantly related to the mean term of hospitalization (P<0.001). The mortality rate was significantly different between different groups of blood types AB (OR=3.50, 95% CI=1.01-12.13, P=0.048). There were no significant differences between the other blood group patient groups (P>0.05). Also, among the clinical symptoms, the prevalence of cough, diarrhea, headache, joint pain, and abdominal pain was higher in people with anti-A antibodies.   Conclusion: The results of the study showed that patients with blood group O did not have a high mortality rate, despite a long hospitalization duration, and blood group AB was at higher risk of infection and mortality compared to other blood groups.