The Effectiveness of Rivandi Syrup on Non-Alcoholic Fatty Liver Disease (NAFLD): A Double Blind Randomized Clinical Trial
نویسندگان
1 Department of Traditional Medicine, School of Traditional Medicine, Tehran University of Medical Science, Tehran, Iran
2 Department of Epidemiology and Biostatistics, Faculty of Medicine, Kurdistan University of Medical Sciences, Sanandaj, Iran
3 Department of Traditional Medicine, School of Traditional Medicine, Tehran University of Medical Science, Tehran, Iran
4 Middle East Liver Disease Center, Tehran, Iran
5 Iranian Research Center for HIV/AIDS, Iranian Institute for Reduction of High-Risk Behaviors, Tehran University of Medical Sciences, Tehran, Iran
6 Research Development Center, Arash Women Hospital, Tehran University of Medical Sciences, Tehran, Iran
7 Department of Traditional Pharmacy, School of Traditional Medicine, Tehran University of Medical Science, Tehran, Iran
doi
10.22034/ircmj.2024.465691.1275چکیده
Background and Objectives: Few studies have been done on the medicinal plant Rivand. Considering the high prevalence of non-alcoholic fatty liver disease (NAFLD) and its complications and ineffective treatments, this study was conducted with the aim of investigating the effectiveness of this traditional Iranian herb in confirmed cases of NAFLD by fibroscan. Methods: The present clinical trial study was conducted in the clinics of Tehran University of Medical Sciences. A total of 61 individuals, consisting of 34 participants in the intervention group and 27 participants in the control group, were included in the study. The participants were randomly assigned using a blocked randomization method. Results: ANCOVA results between two groups for weight (P = 0.015), BMI (P = 0.009), TG (P = 0.001), cholesterol (P = 0.006), AST (P = 0.005) and Hepatic steatosis (P ≤ 0.001) showed a significant relationship. Conclusion: Rivandi Syrup a role in improving NAFLD. So, traditional medicine and prescribing practices should also be taken into consideration.
