Evaluating the Efficiency of Predictive Value of Hematological and Laboratory Indices in Complication of Heart Surgery: A Single Center Retrospective Study
نویسندگان
1 Department of Cardiology, School of Medicine, Seyedoshohda Hospital, Urmia University of Medical Sciences, Urmia, Iran
2 Lorestan University of Medical Science, Lorestan, Iran
3 Blood Transfusion Research Center, High Institute for Research and Education in Transfusion Medicine, Iranian Blood Transfusion Organization (IBTO), Tehran, Iran
4 Department of hematology and blood banking. Faculty of medicine. Mashhad University of medical sciences, Mashhad, Iran
5 Rajaie Cardiovascular Medical and Research Center, School of medicine, Iran University of Medical Sciences, Tehran, Iran
6 Thalassemia & Hemoglobinopathy Research Center, Health Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
7 Department of Medical Laboratory Sciences, School of Allied Medical Sciences, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
8 Department of Biology, Dezful Branch, Islamic Azad University, Dezful, Iran.
9 Department of Anesthesia, Pain Research Centre, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran
doi
10.22034/ircmj.2024.200174چکیده
Background and Objectives: Surgery is one of the treatment manners for patients with cardiovascular disease (CVD). Acute kidney injury (AKI) is a complication that occurs in patients after surgery. In this study, we examined the role of diagnostic value of PLR, NLR, and HbCr in patients undergoing heart surgery. Methods: This retrospective study was performed on patients, who underwent elective open-heart surgery; they referred to Imam Khomeini Hospital of Ahvaz during November 2014 to March 2017. The number of participants was 235 individuals. Laboratory indexes including hematological parameters, biochemical, and demographic data of patients were collected and recorded. Patients were divided into two groups based on surgical outcomes including AKI and atrial fibrillation. An independent sample t-test was also used to measure the quantitative data during the period between pre and post-operative. Pearson correlation was also used to examine the relationship between the measured factors. In order to quantify the strength of associations and their statistical significance, as well as account for negative associations, odds ratios and chi-squared/Fisher’s exact test were performed. P < 0.05 was considered as a significant level. Results: The results showed that the HbCr index was significant before and after the surgery in both groups. In addition, the PLR index also had a suitable diagnostic value for determining AKI in patients after discharge. Furthermore, in determining AKI, PLR had higher diagnostic value and sensitivity compared to NLR. Conclusion: In general, it can be said that HbCr and NLR can be a suitable and available factors to evaluate patients undergoing cardiac surgery for the occurrence of AKI after surgery.
