فهرست نشریات علمی دسترسی آزاد ایران

Background: This research examined the effect of a period of resistance-power training and vitamin D supplementation on serum insulin-like growth factor 1 (IGF-1) concentration and physical function in elderly women. Objectives: This study aimed to evaluate the effect of 12 weeks of resistance-power training and vitamin D supplementation on serum IGF1, vitamin D concentrations, and physical function of elderly women. Methods: In total, 44 elderly volunteered women were randomly assigned to four groups of training+placebo (TP), training+vitamin D (TS), vitamin D (Vit D), and placebo (P). The training groups performed a weight training program for 12 weeks (three sessions per week). People in the Vit D group took one 50,000 IU vitamin D jelly tablet every two weeks, and the P group took one placebo capsule (rice flour). Blood samples were taken from all subjects before and after training; moreover, serum vitamin D, IGF-1, and physical function indices were measured in this study. Data were analyzed in SPSS (version 25) and R3.5.2 software through the analysis of variance of weighted repeated measures. Results: Serum vitamin D was significantly increased in the TS and Vit D groups in comparison with the control group, while it is meaningfully decreased in the TP group (P≤0.05). Training and supplementation interventions had no significant effects on serum IGF-1 (P≥0.05). There was a significant increase in the physical function indices of the TS and TP groups, compared to those in the control group (P≤0.05); meanwhile, there was no significant difference between the two groups. Conclusion: Resistance-power training in the elderly improved the physical function indices; however adding vitamin D supplementation to the training had no significant effect on physical function.