Folliculotropic Mycosis Fungoides with Comedonal-like Appearances
نویسندگان
1 Department of Dermatopathology, Razi Hospital, Tehran University of Medical Sciences, Tehran, Iran
2 Department of Dermatopathology, Razi Hospital, Tehran University of Medical Sciences, Tehran, Iran
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چکیده
Introduction: Folliculotropic mycosis fungoides (FMF) is a variant of mycosis fungoides characterized by the presence of folliculotropicatypical Tcells infiltrates, often with sparing of the epidermis and preferential involvement of the head and neck. Since theoriginal designation of folliculotropic mycosisfungoides (FMF) is a distinct entity, there has been an increasing appreciation of thebroad clinical and histopathology spectrum, which can present in this disease.Case Presentation: In July 2013, a 37-year-old male from Tehran (Iran) who had complained of 9 months of progressive erythematousfollicular patches and plaques on the trunk and comedones and acne like lesions on his forehead has been referred to us. Thehistopathology studyshowedperifollicularandintrafollicular lymphoid cells infiltration predominantly. There wasnohistopathologyevidence of dermal mucin deposit (PAS negative) and alopeciaor syringotropism T cell infiltration. The immunohistochemicalanalysis was positive for CD3 and D4. The patients received different treatments based on the stage of their disease.Conclusions: FMF should be considered in patients who present with alopecia, acne like lesions, cysts and comedones in older ageswith a spectrum of histologic changes. We emphasize for any time it should be under-recognized.