Case Report of a Patient Undergoing Peritoneal Dialysis with Encapsulating Peritoneal Sclerosis Superimposed With Calciphylaxis
نویسندگان
1 Department of Family Medicine, Cheng Ching General Hospital, Taichung, Taiwan
2 Division of Nephrology, Department of Medicine, Taichung Veterans General Hospital, Taichung, Taiwan
3 Division of Nephrology, Department of Medicine, Taichung Veterans General Hospital, Taichung, Taiwan
4 Division of Nephrology, Department of Medicine, Taichung Veterans General Hospital, Taichung, Taiwan
doi
چکیده
Encapsulating peritoneal sclerosis (EPS) is a rare but devastating complication of peritoneal dialysis (PD). Tamoxifenhas been generally well-tolerated, even without randomized controlled trials.Case Presentation: Herein, we report a case of a patient undergoing 12 years of PD who developed EPS and calciphylaxis simultaneously.We also provide a comprehensive discussion about the association between EPS and calciphylaxis. Moreover, althoughtamoxifen is used in EPS due to its inhibition of fibroblast-transforming growth factor beta (TGF ) production, it may worsen thecalciphylaxis due to a hypercoagulable state.Conclusions: We suggest avoiding the use of tamoxifen for EPS in patients with superimposed calciphylaxis.
