Cardiovascular Disease Risk Factors Profile in Individuals With Diabetes Compared With Non-Diabetic Subjects in North-East of Iran
نویسندگان
1 Department of Community Medicine, School of Medicine, Mashhad University of Medical Sciences, Mashhad, IR Iran
2 Department of Community Medicine, School of Medicine, Mashhad University of Medical Sciences, Mashhad, IR Iran
3 Department of Community Medicine, School of Medicine, Mashhad University of Medical Sciences, Mashhad, IR Iran
4 Department of Health, Mashhad University of Medical Sciences, Mashhad, IR Iran
5 Department of Health, State Health Center, Mashhad University of Medical Sciences, Mashhad, IR Iran
6 Department of Health, State Health Center, Mashhad University of Medical Sciences, Mashhad, IR Iran
doi
چکیده
Background: Diabetes mellitus is assumed to be a strong risk factor for cardiovascular diseases (CVD) and is frequently associatedwith other CVD risk factors.Objectives: The aims of this study were to assess the prevalence of different patterns of dyslipidemia in individuals with diabetescompared with non-diabetic subjects and evaluate other accompanied CVD risk factors between the two groups.Patients and Methods: This was an analytical cross-sectional study on 230 participants, aged 28 - 66 years old, who were referredto different urban health centers of Khorasan Razavi province (north-east of Iran). Data from the participants were collected duringtheir first visit by primary care physicians. Statistical package for social science (version 11.5) was used to analyze the data. The chisquareor Fisher’s exact, student’s t or the Mann-Whitney U and correlation tests were used in the analysis.Results: The age and gender of the participants were not different between the two groups (P = 0.1 and P = 0.4, respectively). Themost common patterns of dyslipidemia in both groups were isolated dyslipidemia followed by combined dyslipidemia. Prevalenceof dyslipidemia as a whole (one, two or three lipid profile abnormalities) in patients with diabetes and non-diabetic participantswas 89.3% and 82.6%, respectively and the difference between the two groups was not statistically significant (P = 0.1). Subjects withdiabetes had higher systolic blood pressure (P < 0.001), higher diastolic blood pressure (P = 0.002) and higher body mass index (P= 0.09) compared to non-diabetics. Moreover, they were more likely to have higher levels of total cholesterol (P = 0.01), triglycerides(P = 0.001) and low density lipoprotein cholesterol (P = 0.009) and lower levels of high density lipoprotein cholesterol (P = 0.2).Conclusions: Cardiovascular diseases risk factors are more common in patients with diabetes; however, non-diabetic individualsalso had a high prevalence of risk factors in our region, predisposing them to diabetes. Therefore, further attention by the medicalcommunity is necessary to choose effective strategies for a more a aggressive approach to prevent and manage these risk factors.
