Heart Attack in the Course of Lithium Overdose

نویسندگان

1 Department of Emergency Medicine, Recep Tayyip Erdogan Univercity Faculty of Medicine, Rize, Turkey

2 Department of Emergency Medicine, Haseki Education And Research Hospital, Istanbul, Turkey

3 Department of Cardiovascular Surgery, Dicle Univercity Faculty of Medicine, Diyarbakır, Turkey

4 Department of Emergency Medicine, Recep Tayyip Erdogan Univercity Faculty of Medicine, Rize, Turkey

5 Department of Emergency Medicine, Recep Tayyip Erdogan Univercity Faculty of Medicine, Rize, Turkey

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چکیده

Introduction: Lithium overdose can be associated with cardiac toxicity, especially in those with underlying heart disease. Toxiclevels of serum lithium are associated with cardiotoxic effects ranging from simple ECG disorders to dysrhythmias, cardiomyopathyand even acute myocardial infarction (AMI). This report describes a patient with AMI accompanied by high blood levels of lithium.Case Presentation: A 62-year-old woman was admitted to the emergency department due to weakness and acute chest pain. HerECG revealed ST elevation in leads DI, aVL and V5-6, with a ventricular rate of 80 bpm. Blood chemistry and complete blood countwere within normal limits. The patient’s blood lithium level was measured as 2.3 mmol/L (N: 0.5 - 0.8 mmol/L), and her troponinI level was 0.892 ng/mL (N: 0 - 0.01 ng/mL). Coronary angiography produced normal findings, concurrent with the resolution ofelectrocardiographic abnormalities following elimination of lithium. The clinical course in the intensive care unit was uneventfuland the patient was discharged on the seventh day.Conclusions: Lithium intoxication should be considered in the differential diagnosis, especially in elderly patients on lithium therapywho are admitted to the emergency department with chest pain.