The Relationship Between Depression and Metabolic Syndrome: Systematic Review and Meta-Analysis Study

نویسندگان

1 MSc in Nursing, Kurdistan University of Medical Sciences, Sanandaj, IR Iran

2 Department of Nursing, Faculty of Nursing and Midwifery, Tabriz University of Medical Sciences, Tabriz, IR Iran

3 Department of Biostatistics, Prevention of Psychosocial Injuries Research Center, Ilam University of Medical Sciences, Ilam, IR Iran

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چکیده

Context: Several studies have been conducted on the relationship between depression and metabolic syndrome, which have hadconflicting results. The purpose of this study was a meta-analysis of studies that have examined the relationship between these twovariables.Evidence Acquisition: This meta-analysis systematically reviewed the relationship between depression and metabolic syndrome.Scientific databases including IranMedex, SID, Magiran, Scopus, PubMed, Google Scholar, and Science Direct were searched and 17articles were extracted from 2000 to 2014. Selected studies data were analyzed using meta-analysis and random effects model. Heterogeneitybetween the studies was examined using I2. Data were analyzed using STATA software version 12.1.Results: Seventeen studies were analyzed with a sample size of 31880 people. Analysis by the type of studies showed that the relationshipbetween the two variables in cross-sectional studies (OR = 1.51, CI 95% = 1.36 - 1.68) and cohort studies (OR = 1.6, CI 95% = 1.23- 2.08) was significant. In general, the heterogeneity test results among the studies was not significant (P for heterogeneity = 0.08,I2 = 39.8%).Conclusions: There is a relationship between depression and metabolic syndrome.