Campylobacter jejuni Bacteremia in a Patient With Acute Lymphocytic Leukemia
نویسندگان
1 Professor Alborzi Clinical Microbiology Research Center, Nemazee Hospital, Shiraz University of Medical Sciences, Shiraz, IR Iran
2 Professor Alborzi Clinical Microbiology Research Center, Nemazee Hospital, Shiraz University of Medical Sciences, Shiraz, IR Iran
3 Professor Alborzi Clinical Microbiology Research Center, Nemazee Hospital, Shiraz University of Medical Sciences, Shiraz, IR Iran
4 Professor Alborzi Clinical Microbiology Research Center, Nemazee Hospital, Shiraz University of Medical Sciences, Shiraz, IR Iran
5 Department of Microbiology, School of Medicine, Gonabad University of Medical Sciences, Gonabad, IR Iran
doi
چکیده
Introduction: Campylobacter jejuni is a slender, motile, non-spore-forming, helical-shaped, gram-negative bacterium. It isoneof themost common causes of human gastroenteritis in the world. The aim of this study was to present a patient with acute lymphocyticleukemia (ALL), who was infected with Campylobacter jejuni.Case Presentation: We describe the medical records of a pediatric ALL patient with bacteremia caused by C. jejuni, who was diagnosedat Amir hospital, Shiraz, Iran. This 14-year-old male visited the emergency department of Amir hospital with night sweats,severe polar high-grade fever, reduced appetite, and nausea in August 2013. Given the suspected presence of an anaerobic or microaerophilicmicroorganism, aerobic and anaerobic blood cultures were performed using an automated blood cultivator, theBACTEC 9240 system. In order to characterize the isolate, diagnostic biochemical tests were used. Antibiotic susceptibility testingwas done with the disk diffusion method. The primary culture was found to be positive for Campylobacter, and the subculture ofthe solid plate yielded a confluent growth of colonies typical for Campylobacter, which was identified as C. jejuni by morphologicaland biochemical tests. The isolate was resistant to ciprofloxacin, cefotaxime, cephalexin, piperacillin/tazobactam, nalidixic acid,aztreonam, cefuroxime, cefixime, ceftazidime, and tobramycin.Conclusions: C. jejuni should be considered in the differential diagnosis as a potential cause of bacteremia in immunosuppressedpatients. In caseswheretheBACTECresult is positive in aerobic conditions but the organism cannot be isolated, ananaerobic culturemedium is suggested, especially in immunocompromised patients.
