Treatment Following Intoxication With Lethal Dose of Paraquat: A Case Report and Review of Literature
نویسندگان
1 Student Research Committee, School of Medicine, Shiraz University of Medical Sciences, Shiraz, IR Iran
2 Department of Infectious Diseases, Gastroenterohepatology Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran
3 Student Research Committee, School of Medicine, Shiraz University of Medical Sciences, Shiraz, IR Iran
doi
10.5812/ircmj.19373چکیده
Introduction: Paraquat is a widely used nitrogen-based herbicide which is lethal and causes multi-organ failure by accumulation in cells, which subsequently leads to death.Case Presentation: The present case report introduced a 25-year-old male with nausea, vomiting, and severe substernal burning sensation after incidentally ingestion of a large amount of paraquat. The treatment of the patient with antioxidants (N-acetylcysteine and vitamin E) and hemodialysis started immediately after arriving to the hospital.Conclusions: Immediate and adequate use of antioxidants and hemodialysis has an undeniable and important role in survival of patients after ingestion of a large amount of paraquat.
