فهرست نشریات علمی دسترسی آزاد ایران

Background: Demographic factors, hospital status, and comorbidities affect the mortality of patients with coronavirus disease (COVID-19).Aim: This cross-sectional study was performed with aim to evaluate the mortality predictors of hospitalized COVID-19 patients in northeastern Iran (Mashhad city).Method: In this retrospective study, the electronic records (demographic data, clinical variables, and comorbid conditions) of survived and non-survived hospitalized COVID-19 patients were searched from March 2021 to March 2022 during six pandemic waves.Results: Analysis of 59099 hospitalized COVID-19 patients showed the mean age of 54.4722.5 years (female: 46.92%). Binary logistic regression analysis showed that age, masculinity, respiratory distress, and loss of consciousness among demographic data and clinical variables significantly contributed to mortality (OR>1, P<0.05). Diabetes, cancer, respiratory diseases, kidney diseases, and immunodeficiency diseases increased the chance of death. High SpO2 (>93) protected against death (OR<1, P<0.05).Implications for Practice: The results of the present study revealed that the clinical outcome of COVID-19 infection is highly affected by demographic, clinical, and comorbidity factors. Several factors including age, masculinity, respiratory distress, loss of consciousness, diabetes, cancer, respiratory, kidney and immunodeficiency diseases had a risk effect on COVID-19 death during six pandemic waves. Also, high SpO2 (>93) was detected as a protective factor for death followed by COVID-19 infection.