Latent and Active Tuberculosis: Evaluation of Injecting Drug Users
نویسندگان
1 Department of Infectious Diseases, Hamedan University of Medical Sciences, Hamedan, IR Iran
2 Department of Infectious Diseases, Hamedan University of Medical Sciences, Hamedan, IR Iran
3 Department of Social Medicine, Hamedan University of Medical Sciences, Hamedan, IR Iran
4 Hamedan University of Medical Sciences, Hamedan, IR Iran
5 Hamedan University of Medical Sciences, Hamedan, IR Iran
doi
چکیده
Background: There is a high risk of tuberculosis (TB) infection among injecting drug users (IDUs).Objectives: This study aimed to determine the frequency of latent and active TB infection among IDUs.Materials and Methods: In a cross-sectional study between 2008 and 2009, IDUs referred to the methadone maintenance treatment(MMT) centers in Hamedan-Iran, undergone tuberculin skin test (PPD; purified protein derivative) were recruited. The participants with positive results for PPD test (> 5 mm and > 10 mm in HIV positive and negative cases), undergone other complementary procedures such as chest-X-ray and sputum smear test.Results: Overall, 268 IDUs between 18 and 70 (mean: 34.5 [8.2]) years were included in the study. PPD test had positive findings in 49 cases(18.3%). There was no significant difference of PPD positivity between HIV positive and negative participants (17.7% vs. 18.5%). An active TB was found among IDUs.Conclusions: The high prevalence of latent and active TB among IDUs indicates the need for TB screening tests among this population.
