Attenuation of Cardiovascular Responses and Upper Airway Events to Tracheal Extubation by Low Dose Propofol
نویسندگان
1 Department of Anesthesiology and Critical Care Research Center, Shiraz University of Medical Sciences, Shiraz, IR Iran
2 Department of Anesthesiology, Faghihi Hospital, Shiraz University of Medical Sciences, Shiraz, IR Iran
3 Department of Anesthesiology, Faghihi Hospital, Shiraz University of Medical Sciences, Shiraz, IR Iran
4 Department of Anesthesiology, Faghihi Hospital, Shiraz University of Medical Sciences, Shiraz, IR Iran
5 Shiraz University of Medical Science, Shiraz, IR Iran
doi
چکیده
Background: Hemodynamic changes and respiratory tract complications are often followed by tracheal extubation. These events may be dangerous in neurosurgical patients and those with cardiovascular disease or at an old age.Objectives: The aim of this study is to investigate the attenuation of cardiovascular responses and upper airway events resulting from tracheal extubation by low dose propofol.Materials and Methods: 80 patients with ASA physical status I, undergoing an elective surgery in a double blind manner received 0.5mg/kg propofol or normal saline 2 minutes before extubation. Heart rate and blood pressure and quality of tracheal extubation were recorded.Results: Heart rate and blood pressure in patients receiving propofol were less than the control group (P < 0.05) at the time of injection of propofol, but there were no differences between the two groups at the time of extubation.Conclusions: We concluded that propofol can reduce SBP, DBP, MAP, HR & cough production at the time of injection but there were no significant changes in these parameters after extubation.
