Effect of Herbal Therapy to Intensity Chemotherapy-Induced Nausea and Vomiting in Cancer Patients.

نویسندگان

1 School of Nursing and Midwifery, Shahroud University of Medical Sciences, Shahroud, IR Iran

2 School of Pharmacy, Tehran University of Medical Sciences, Tehran, IR Iran

3 School of Nursing and Midwifery, Shahroud University of Medical Sciences, Shahroud, IR Iran

4 Clinical Research Development Center, Qom University of Medical Sciences, Qom, IR Iran

5 School of Nursing and Midwifery, Guilan University of Medical Sciences, Rasht, IR Iran

6 School of Nursing and Midwifery, Shahroud University of Medical Sciences, Shahroud, IR Iran

doi
چکیده

Background: Chemotherapy-induced nausea and vomiting are the most important complications for cancer patients as its prevalence has been reported to be about 54-96 percent. ginger has been used for medicinal purposes including nausea and vomiting in traditional Persian, Chinese and Indian pharmacopoeia.Objectives: The objective of this study was to evaluate the efficacy of complimentary ginger among cancer patients experiencing nausea and vomiting.Material and Methods: A randomized cross-over clinical trial was carried out on patients under chemotherapy treatment for at least 2 episodes of chemotherapy and at least 2 episodes of previous experience of nausea and vomiting. Subjects of this study received 2 different complementary regimes with 250mg ginger capsule in regime A and placebo capsule in regime B. subjects of the study were crossed over to receive the other regime during the two cycles of chemotherapy.Results: Findings of the study indicated that subjects receiving ginger showed significant reduction in frequency and intensity of nausea and vomiting compared to placebo receiving subjects.Conclusions: According to finding of this study, in accordance to most of other researches, ginger is an effective agent to reduce chemotherapy- induced nausea and vomiting. However, there are some researches supporting ginger as a moderate antiemetic agent among cancerous patients under chemotherapy.

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