Ovarian Cyst Enlargement in a 14 Year Old Female with Persistent Ascities, Severe Hypothyroidism and Elevated Serum CA-125 Level

نویسندگان
Eftekhari, K ID 1
Motamed, F ID 2
Kiani, MA ID 3
Rabbani, A ID 4

1 Department of Pediatrics, Mousavi Hospital, Zanjan University of Medical Sciences, Zanjan

2 Department of Gastroenterology, Children's Medical Center Hospital, Tehran University of Medical Sciences, Tehran

3 Department of Gastroenterology, Children's Medical Center Hospital, Tehran University of Medical Sciences, Tehran

4 Department of Endocrinology, Children's Medical Center Hospital, Tehran University of Medical Sciences, Tehran, Iran

doi
چکیده

 A 14 year old female complained of abdominal pain and distention with vomiting. The physical exam showed thyroid enlargement and ascites. The imaging evaluation demonstrated a large ovarian cyst. Laboratory tests depicted hypothyroidism and marked elevation of Carbohydrate antigen 125 (CA-125) levels. As the bone age was 10 years, more retarded than the chronological age, Van Wyk and Grumbach syndrome was suspected. Treatment with thyroid hormone was initiated and the condition improved dramatically with disappearance of symptoms and signs 5 weeks later. 

کلیدواژه‌ها
Ovarian cyst, Hypothyroidism, CA-125, Van Wyk and Grumbach syndrome