فهرست نشریات علمی دسترسی آزاد ایران

Hepatitis B virus (HBV) infection, one of the major health priorities, accounts approximately for 350 millionchronic cases and a global total of 33 million people were living with human immunodeficiency virus (HIV) in theworld. Co-infection with HIV and the HBV presents a significant challenge to health care providers, with differentprevalence rates in different parts of the world. It is important to screen all HIV infected individuals for HBV infectionand reverse. Infection with HBV becomes more violent in patients co-infected with human immunodeficiencysyndrome. HIV/HBV co-infected individuals are at increased risk of chronic hepatitis, cirrhosis, and hepatocellularcarcinoma, and of experiencing HAART toxicity. In this review, the latest statistics on epidemiology of HIV, HBVand their co-infection has been presented along with prominent characteristics of HBV. Transmission routeswhich are the common between HBV and HIV are described and the most important ones are described accordingto the regional and age features. Also, there is a series of actions being performed once HBV infections occurto prevent HIV or to diagnose if the HBV-infected individuals are also infected with HIV. As in treatment case,some of the frequent treatment methods including applying interferon and using nucleoside and nucleotide analogueshave been discussed. Finally, we would explain the new recommendations for treating patients who wereco-infected with HBV and HIV, including staging HBV and HIV treatment, based on the stage of each disease. Italso outlines the optimal treatment options, whether the patient is treated for HBV first, HIV first, or HIV and HBVtogether.