فهرست نشریات علمی دسترسی آزاد ایران

Anthracosis is the black pigment discoloration of bronchi with an unknown cause which can causebronchial destruction and deformity (anthracofibrosis). The objective of this study was to determine the frequencyof tuberculosis in anthracosis and evaluate their association.Methods: One hundred and twenty subjects with bronchoscopy diagnosis of simple anthracosis, anthracofibrosisand non-anthracotic control groups entered this study. Demographic data and important clinical and radiologicalfindings were recorded. Bronchial biopsy and bronchoalveolar lavage were performed for further cytopathological,acid-fast bacilli staining and culture in all cases.Results: Cough and dyspnea were significantly higher in anthracosis subjects. Radiological characteristic oftuberculosis such as upper lobe localization and cavity were not significantly higher in anthracosis subjects thatsuffer from tuberculosis. Laboratory test for tuberculosis showed positive acid fast bacilli in 17.5 and 25% andcaseating granuloma in 20 and 17.5% of anthracosis and anthracofibrosis subjects. Adding the result of culture,the frequency of tuberculosis in both groups of anthracosis was 27.5% that was significantly more than nonanthracoticcontrol group (Odd ratio= 6.15, CL=1.29<OR<40.06).Conclusion: Anthracosis and tuberculosis showed a significant association. Anti-tuberculosis therapy promisedbetter treatment of anthracosis in subjects proved to suffer from tuberculosis.