Simultaneous Pattern Visual Evoked Potential and Pattern Electroretinogram in Strabismic and Anisometropic Amblyopia
نویسندگان
1 Department of Optometry, School of Paramedical Sciences,
2 Department of Social Medicine, School of Health, Mashhad University of Medical Sciences, Mashhad, Iran
3 Department of Optometry, School of Paramedical Sciences,
4 Department of Optometry, School of Paramedical Sciences,
5 Department of Optometry, School of Paramedical Sciences,
6 Department of Optometry, School of Paramedical Scienc2Eye Research Center, Khatam Anbia Hospitales,
doi
چکیده
Background: Amblyopia is a relatively common condition in which visual acuity through an eye is subnormaldespite no overt pathology. Pattern visual evoked potential (PVEP) can detect any defect from optic nerve tooccipital cortex and pattern electroretinogram (PERG) can detect retinal defects specially the ganglion layers.This study was performed to evaluate the cortical and retinal activity in strabismic and anisometropic amblyopia.Methods: PVEP and PERG were recorded simultaneously in 40 amblyopes (20 strabismics and 20 anisometropics)and 20 normal control subjects. Normal subjects were age and sex matched with patients.Results: The P100 latency in PVEP was increased in both groups of patients but the P100 amplitude was reducedonly in anisometropic group. In PERG, the amplitude of P50 was reduced in all patients with no significantchange in latency.Conclusion: Beside reduced PVEP responses in strabismic and anisometropic amblyopia, the activity of retinareduced too. It is likely that retinal impulses can affect the development of visual system.
