فهرست نشریات علمی دسترسی آزاد ایران

Background: With a high rate of death and morbidity, oral cancer ranks as the sixteenth most prevalent cancer worldwide. According  to the Global Cancer Observatory (GLOBOCAN) of the International Agency for Research on Cancer (IARC), there were 177,757  oral cancer-related deaths and 377,713 new cases globally in 2020. Oral cancer in India comprises 45% of the global disease burden. Men (incidence rate: 13.1 per 100,000) are 2.62 times more likely to be affected by head and neck cancer than women (5 per 100,000) and experience double the corresponding mortality rates. The high prevalence, incidence, and excruciating nature of the disease necessitated this review to outline potential precautions and prophylactic interventions to be undertaken to prevent this agonizing and highly fatal disease in order to sensitize healthcare workers and train them to fight this disease.Methods: The search analysis from PubMed, the World Health Organisation (WHO) International Clinical Trials Registry, Cochrane Reviews, and CENTRAL yielded a list of comprehensive strategies used in different geographic locations to prevent this deleterious health issue. Results: The results include evidence of interventions that have successfully prevented oral cancer in different sections of the population. In addition to controlling tobacco use and herpes virus infection, these interventions include community health programs, primary healthcare workers and dentists, chemopreventive agents, herbal extracts, and artificial intelligence models. Conclusion: Oral health is one factor affecting well-being, so a preventive approach must be considered to ensure its achievement.