Evaluation of the synergistic antibacterial effect of chlorhexidine solution 0.2% and phosphoric acid gel 37% against Streptococcus mutans during fissure sealant therapy: An in vitro study
نویسندگان
1 Department of Pediatric Dentistry, Dental Faculty, Kerman University of Medical Sciences, Kerman, Iran
2 Department of Pediatric Dentistry, Dental Faculty, Kerman University of Medical Sciences, Kerman, Iran.
3 Department of Pediatric Dentistry, Dental Faculty, Kerman University of Medical Sciences, Kerman, Iran.
4 Department of Endodontics, Dental Faculty, Kerman University of Medical Sciences, Kerman, Iran.
5 Oral and Dental Diseases Research Center, Kerman University of Medical Sciences, Kerman, Iran.
6 Imam Reza Dental Clinic, Kazeroun, Iran.
7 Associate Professor, Kerman Oral and Dental Diseases Research Center, Department of Pedodontics, School of Dentistry, Kerman University of Medical Sciences, Kerman, Iran
doi
10.34172/johoe.2309.1593چکیده
Background and Objective: Pit and fissure sealant therapy is widely used to prevent caries of the occlusal surfaces of posterior teeth. In this treatment, failure is not uncommon. Aim of this study was evaluation of the effects of chlorhexidine solution 0.2% and phosphoric acid gel 37% against Streptococcus mutans to synergize each other's effect on fissure sealant therapy for reducing of risk of the failure. Method: The antibacterial effect of two materials was evaluated by Disc Diffusion method. For checking of accuracy of the test, was used the positive control disck and the negative control disck. SPSS26 statistical software was used for data analysis. Descriptive statistics were used to describe the bacterial inhibition halo. Results: Phosphoric acid gel 37% showed significant antibacterial effects. The antibacterial effects of Chlorhexidine 0.2% solution were also comparable to the positive control disc. Conclussion: Application of chlorhexidine solution on the occlusal surfaces shortly before the start of the sealant therapy process can further reduce the number of bacteria. This can reduce the risk for occurrence of decay under the sealant.
