Endometrial Stromal Sarcoma Presented with Galactorrhea

نویسندگان

1 Department of Endocrinology, Mazandaran University of Medical Sciences, Sari, Iran

2 Department of Endocrinology, Mazandaran University of Medical Sciences, Sari, Iran

3 General Practitioner, Medical Researcher, Imam Khomeini Hospital, Sari, Iran

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چکیده

 Sarcomas are rare forms of endometrial (uterine) cancer. We report here a 52 years old woman who was hospitalized due to abnormal uterine bleeding (menorrhagia). The patient underwent total abdominal hysterectomy, bilateral salpingo-oophorectomy and para-iliac lymphadenectomy. The pathological result was endometrial stromal sarcoma/low grade. Meanwhile, she had an ESR of 80 mm/h. After 4 years, the patient referred with dyspnea and galactorrhea. Her serum prolactin level was more than 100 ng/ml. The lung CT-scan revealed metastatic lesions. Brain MRI with hypophysis view was normal. Thus chemotherapy with CYADIC regimen was begun for her and her ESR reached 13. Also, a decline in prolactin level occurred. After 2 years,she was hospitalized for abdominal pain and the assessments revealed progressive metastasis of the abdomen and whole body scan demonstrated the metastatic bone disease. Also, prolactin level highly increased(11102 mIu/Lit). The MRI of the brain was normal again. Serum macroprolactin was measured, revealing anegative result. The ESR reached 80 mm/h.