فهرست نشریات علمی دسترسی آزاد ایران

Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer among menin the developed world. The objective of this study was to document the gender, age, sites of occurrence andhistological differentiation of the HNSCC in southern Iran.Methods: In a retrospective study from 1992 to 2007, 386 patients with a histological diagnosis of the HNSCCwere investigated in departments of pathology of Shiraz Dental School and Khalili Hospital in southern Iran.Results: Among 386 cases, there were 289 male (74.9%) and 97 female (25.1%). In younger patients, the maleto female ratio was lower than that in the older ones. The larynx was the most commonly affected site (44%),followed by the oral cavity (34.7%), skin (7%), oropharynx (3.1%), hypopharynx (2.9%), cervical esophagus(2.3%), other sites (4.2%) and unknown site (1.8%). 45.6% were well but 8.3% were poorly differentiated forSCC.Conclusion: HNSCC was most common in the larynx and oral cavity with an older aged male preponderance,but male to female ratio was lower in younger patients than older ones.