فهرست نشریات علمی دسترسی آزاد ایران

Amblyopia is a relatively common condition with an incidence of 2-2.5% in which visual acuitythrough an eye is subnormal despite no overt pathology. The use of pattern visual evoked potential (P-VEP) hasbeen the primary technique for electrophysiologically detecting amblyopia in patients unable to undergo conventionaltesting. This study was performed to evaluate the effectiveness of P-VEP parameters in amblyopic patientsunder monocular and binocular conditions.Methods: Visual function was measured using P-VEP and Snellen acuity test in 30 children with amblyopia (12strabismic and 18 anisometropic amblyopes) and 30 visually normal control subjects.Results: Totally, visual evoked potentials elicited by high contrast small checkerboard patterned stimuli weresignificantly reduced in amplitude and prolonged in latency in amblyopic eyes. The mean intraocular amplitudedifference was significantly larger in amblyopics than in normal groups. There was also no difference betweenthe healthy eye in the amblyopic group and the control one. On binocular viewing, the amount of VEP amplitudewas significantly greater in normal subjects than that in both amblyopic groups. Regarding the type of amblyopia,the mean binocular VEP amplitude as compared to that in the non-amblyopic eye was greater for the anisometropicthan the strabismic groups.Conclusion: In both amblyopic groups, the VEP responses were significantly reduced in amplitude and prolongedin latency. In binocular viewing, the amount of VEP amplitude was greater in normal subjects than bothamblyopic groups. The mean binocular amplitude was significantly greater for the anisometropic than for thestrabismic group.