فهرست نشریات علمی دسترسی آزاد ایران

Anaplastic thyroid carcinomas are undifferentiated and highly aggressive tumors of the thyroid follicular epithelium,with a disease-specific mortality approaching 100 percent. This study reports ten cases with advancedanaplastic thyroid carcinoma with ineffective surgical interventions. Between 2001-2006, we treated 10 patientswith anaplastic carcinoma of the thyroid. All patients presented with advanced phase and were documented bypathological study. The surgical intervention was thyroidectomy in 3 cases, debunking surgery in other three, justtracheostomy in three cases, and only biopsy in one patient. All of our patients died in 4 days to 8 months aftersurgery. Surgical intervention had no benefit in treatment of advanced anaplastic carcinoma of the thyroid andthe suitable surgical intervention was to maintain an open airway. Early recognition of the disease is essential toallow prompt initiation of therapy. There is no cure for advanced situations, and surgery, radiotherapy, and chemotherapyplay no important role in the treatment.