A Fast and Highly Efficient Protocol for Synthesis of Dihydropyrano[2,3]PyrazoleCompounds Using Acidic Ionic Liquid 3-Methyl-1-Sulfonic Acid Imidazolium Chloride ([Msim]Cl)as Catalyst and Green Solvent
نویسندگان
1 Research Laboratory of Nanoporous Materials, Faculty of Chemistry, Iran University of Science and Technology, Tehran, P.O. Box 16846-13114, Iran.
2 Research Laboratory of Advanced Materials, Chemistry and Chemical Engineering Research Center of Iran, Tehran, P.O. Box 14335-186, Iran.
doi
10.24200/sci.2016.3879چکیده
A new, efficient, and environmentally benign protocol for the one-pot, four-component synthesis of dihydropyrano[2,3-c]pyrazoles by condensation of ethylacetoacetate, hydrazine hydrate, aromatic aldehyde, and malononitrile catalyzed by3-methyl-1-sulfonic acid imidazolium chloride([Msim]Cl) as an ecofriendly catalyst with high catalytic activity and reusability at 30 0C under solvent-free conditions is reported. The reactions proceed to completion within 5–15 min in 87–97% yield.
