فهرست نشریات علمی دسترسی آزاد ایران

Pain management after spinal surgery remains a challenge for patients undergoing posterior spinal fusion (PSF) for adolescent idiopathic scoliosis (AIS). Therefore, in this study, we investigated the consequences and complications of intrathecal morphine injection in posterior fusion surgery for patients with idiopathic scoliosis. In this study, as a single-blind clinical trial, patients who were candidates for posterior fusion surgery for patients with idiopathic scoliosis referred to Imam Khomeini Hospital were enrolled in two groups, with and without intrathecal morphine injection (with randomization). In this study, a total of 60 patients- 30 patients receiving intrathecal morphine injection (56.7% male and 43.3% female with an average age of 21.2 ± 4.9 years) and 30 patients without intrathecal morphine injection (60% male and 40% female with an average age of 19.3 ± 8.8 years) were included in the study. The repeated measures test showed that the average pain during recovery at 6, 12, and 24 hours after the operation exhibited a decreasing trend, and intrathecal morphine injection had a dual effect in reducing the average pain of the pain scores (P < 0.05). The chi-square and Fisher tests revealed that the frequency of nausea, itching, and complications (severe allergic reactions, respiratory distress, or spinal headaches) during the postoperative recovery in patients with intrathecal morphine injection was higher than in those without it; however, the difference was statistically significant (P < 0.05). Intrathecal morphine injection leads to a significant reduction in postoperative pain, a decrease in oxygen use, a reduced need for narcotic drugs, and a shorter duration until the first oral administration, while increasing the hours of pain medication requests. However, it also results in an increase in nausea, itching, and side effects (severe allergic reactions, respiratory distress, or spinal headaches) within 24 hours after surgery.