Pharmacognostic Evaluation, Phytochemical Screening and Antioxidant Potential of Leaves and Stems of Atalantia racemosa Wight
نویسندگان
1 Department of Pharmacology, Gyan Vihar School of Pharmacy, Suresh Gyan Vihar University, Jaipur, Rajasthan, 302017, India
2 Department of Pharmacology, Gyan Vihar School of Pharmacy, Suresh Gyan Vihar University, Jaipur, Rajasthan, 302017, India
3 Department of Pharmacology, Gyan Vihar School of Pharmacy, Suresh Gyan Vihar University, Jaipur, Rajasthan, 302017, India
doi
10.26655/JMCHEMSCI.2024.12.13چکیده
Atalantia racemosa Wight, a plant from the Rutaceae family, is renowned for its medicinal properties, having a long history of traditional use. This study aimed to investigate the pharmacognostic characteristics, conduct a phytochemical screening, and evaluate the antioxidant potential of the leaves and stems of Atalantia racemosa Wight. Leaves and stems of Atalantia racemosa Wight were collected from Kas Pathar, Satara, and authenticated by the Botanical Survey of India. The plant material was extracted using ethanol and water, concentrated, and stored for analysis. Pharmacognostic evaluations included macroscopic and microscopic examination, physicochemical testing (e.g., extractive values, loss on drying, and ash values), phytochemical screening, and antioxidant assays. The results indicated that the leaves had a lower loss on drying (2%) but higher total ash (11.46%) and water-soluble ash (3.98%) compared to stems (4%, 8.6%, and 0.4%, respectively). Leaves also exhibited higher ethanol (10.0%) and water extracts (5.7%) compared to stems (8.0% and 5.0%). However, stems showed a higher acid-insoluble ash (2.66%) and chloroform extract (4.0%) than leaves. Phytochemical screening revealed the presence of alkaloids, terpenoids, steroids, glycosides, saponins, tannins, and flavonoids. Ethanolic extracts of both leaves and stems demonstrated stronger antioxidant activity than their aqueous extracts. The stems of Atalantia racemosa Wight have more bioactive chemicals and antioxidants than the leaves, suggesting medicinal potential. Further research should isolate active molecules and test their efficacy in vivo