Comparative Analysis of Hemoglobin Measurements Using Point of Care Testing (POCT) Hemoglobin Meter and Hematology Analyzer in a Clinical Setting

نویسندگان

1 Dr. Soetomo General Hospital, Surabaya, Indonesia

2 Clinical Pathology Residency Program, Department of Clinical Pathology, Faculty of Medicine, Airlangga University; Dr. Soetomo General Hospital, Surabaya, Indonesia

3 Dr. Soetomo General Hospital, Surabaya, Indonesia

doi
10.48309/jmcs.2024.208866
چکیده

The importance of point-of-care testing (POCT) has increased due to its ability to reduce the turnaround time (TAT), allowing faster patient management and health care. The Prufen Hemoglobin (Hb) Meter, a POCT test strip, measures the blood’s hemoglobin levels. This study aimed to analyze the comparison between the POCT Prufen Hb Meter and a hematology analyzer using the Sodium Lauryl Sulfate (SLS) method. This study was conducted at the Dr. Soetomo Hospital from December 2022 to February 2023. A total of 92 EDTA venous samples from the Sysmex XN 1000 hematology analyzer were divided into three hemoglobin levels: low (<12 g/dL), 30 samples; normal (12-16 g/dL), 32 samples; and high (>16 g/dL), 30 samples. All samples were re-examined using the POCT Prufen Hemoglobin Meter. The t-test analysis showed a significant difference between the two methods (p < 0.05). The Bland-Altmann test indicated a good agreement between the two devices. In conclusion, the Prufen Hb Meter POCT device consistently measured lower hemoglobin values than the Sysmex® XN 1000 across all hemoglobin levels. Therefore, caution is needed when using the POCT device for hemoglobin detection for the purpose of initiating and monitoring therapy. Measurement of hemoglobin levels with a hematology analyzer is recommended for more accurate results.