The maternal and neonatal outcomes of pregnant women with definite COVID-19
نویسندگان
1 Department of Perinatology, Yas Complex Hospital, Tehran University of Medical Sciences, Tehran, Iran
2 Department of Anesthesiology, School of Medicine, Amir Alam Hospital, Tehran University of Medical Sciences, Tehran, Iran
3 Maternal, Fetal, and Neonatal Research Center, Yas Complex Hospital, Tehran University of Medical Sciences, Tehran, Iran
4 Department of Perinatology, Yas Complex Hospital, Tehran University of Medical Sciences, Tehran, Iran
5 Microbiology student of Shahid Beheshti University of Medical Sciences, Tehran, Iran
6 Department of Perinatology, Yas Complex Hospital, Tehran University of Medical Sciences, Tehran, Iran
7 Maternal, Fetal, and Neonatal Research Center, Yas Complex Hospital, Tehran University of Medical Sciences, Tehran, Iran
8 Department of Perinatology, Yas Hospital, Tehran University of Medical Sciences, Maternal, Fetal and Neonatal Research Center, Tehran University of Medical Science, Tehran, Iran.
9 Faculty of Educational and Psychology, Department Of Psychology, University Of Sistan and Baluchestan, Sistan and Baluchestan, Iran
10 Obstetrics and Gynecology Department, Pregnancy Health Research Center, Ali IbneAbitaleb Hospital, Faculty of Medicine, Zahedan University of Medical Sciences, Zahedan, Iran
11 Department of Perinatology, Yas Complex Hospital, Tehran University of Medical Sciences, Tehran, Iran
doi
10.22038/ijp.2022.65843.4962چکیده
Background: This study aimed to assess the symptoms and clinical laboratory data of pregnant women with COVID-19 in their second or third trimester of pregnancy as well as their maternal and neonatal outcomes. Methods: This retrospective observational study was conducted on 177 pregnant women with COVID-19 who were admitted to Yas hospital (affiliated with Tehran University of Medical Sciences), and Ali-ibn-Abi-Talib hospital (affiliated with Zahedan University of Medical Sciences). Results: There was significant higher complaints including fever (p-value=0.015), cough (p-value=0.028), fatigue (p-value=0.002), dyspnea (p-value=0.022), and lower hemoglobin level (p-value=0.009) in patients who were in their third trimester compared to those who were in their second trimester. 9.6% (n=17) of the patients had severe disease and needed ICU admission. There was a significant variation regarding gestational age (p-value=0.022) in pregnant women admitted to ICU compared to the other ones. During the study, delivery happened in 108 (61%) pregnant women. Fetal distress following meconium deification (p-value=0.041), need to MGSO4 (p-value=0.001), IUFD (p-value=0.006), need for blood transfusion (p-value=0.004), and neonatal death (p-value<0.001) were significantly higher in patients who needed ICU admission. Conclusion: Higher gestational weeks are the main risk factor for severe COVID-19 disease. Although vertical transmission is rare; due to the higher risk of perinatal outcomes, the delivery should be done in a center with a NICU department.
