A facile and green three-component synthesis of 2-amino-3-cyano-7-hydroxy-‎‎4H-chromenes on grinding

نویسندگان
Safari, Mostafa ID 1
Javanshir, Shahrzad ID 2
Dekamin, Mohammad G. ID 3

1 Department of Chemistry, Iran University of Science and Technology, Tehran 16846-13114, Iran‎

2 Department of Chemistry, Iran University of Science and Technology, Tehran 16846-13114, Iran‎

3 Department of Chemistry, Iran University of Science and Technology, Tehran 16846-13114, Iran‎

doi
چکیده

A simple, efficient and one-pot method has been developed for the synthesis of densely functionalized aryl derivatives of 2-amino-3-cyano-7-hydroxy-4H-chromene by the domino Knoevenagel-Michael-cyclization reactions of aromatic aldehydes, resorcinol and malononitrile in the presence of a catalytic amount of Na2CO3 under grinding conditions.

کلیدواژه‌ها
Multicomponent reactions (MCRs), Green chemistry, 4H-chromene derivatives, resorcinol, malononitrile