Mortality Rate of COVID‐19 Patients in Intensive Care Unit: A Multicentre Retrospective Observational Study
نویسندگان
1 2Department of Anesthesiology, Faculty of Medicine, Universitas Brawijaya, Indonesia
2 Department of Anesthesiology, Faculty of Medicine, Universitas Brawijaya, Indonesia
3 Department of Anesthesiology, Faculty of Medicine, Universitas Hasanuddin, Indonesia
4 Department of Anesthesiology, Faculty of Medicine, Universitas Sumatera Utara, Indonesia
5 Department of Anesthesiology, Faculty of Medicine, Universitas Sumatera Utara, Indonesia
6 Department of Anesthesiology and Intensive Theraphy, Awal Bros Hospital Batam, Indonesia
7 Department of Anesthesiology, Faculty of Medicine, Universitas Padjadjaran, Indonesia
8 Department of Anesthesiology, Dr. Kariadi Hospital, Faculty of Medicine Diponegoro University, Indonesia
9 Department of Anesthesiology and Intensive Theraphy, Kariadi Hospital Semarang, Indonesia
10 1Department of Anesthesiology and Intensive Care, Faculty of Medicine, Universitas Sumatera Utara, Indonesia
11 2Department of Anesthesiology, Faculty of Medicine, Universitas Brawijaya, Indonesia
12 2Department of Anesthesiology, Faculty of Medicine, Universitas Brawijaya, Indonesia
13 Department of Anesthesiology, Faculty of Medicine, Universitas Sriwijaya, Indonesia
14 Department of Anesthesiology, Faculty of Medicine, Universitas Hasanuddin, Indonesia
15 Department of Anesthesiology, Faculty of Medicine, Universitas Hasanuddin, Indonesia
16 Department of Anesthesiology and Intensive Theraphy, Awal Bros Hospital Batam, Indonesia
17 Department of Anesthesiology and Intensive Theraphy, Awal Bros Hospital Batam, Indonesia
18 Department of Anesthesiology, Dr. Kariadi Hospital, Faculty of Medicine Diponegoro University, Indonesia
19 Department of Anesthesia and Intensive Care, Cipto Mangunkusumo Hospital Faculty of Medicine Universitas Indonesia, Indonesia
20 Department of Anesthesia and Intensive Care, Cipto Mangunkusumo Hospital Faculty of Medicine Universitas Indonesia, Indonesia
doi
10.26655/JMCHEMSCI.2023.4.7چکیده
The case of Coronavirus Disease 2019 (COVID-19) is growing rapidly worldwide. More than 6 million people in Indonesia were confirmed to be infected as of March 2022. This disease caused an increase in the demand of respiratory assistance and intensive care services back in 2021. Unfortunately, the report about COVID-19 case in Intensive Care Unit (ICU) of Indonesia is very scarce although it is very crucial to evaluate the treatment approach and the prognosis of the patients. This study aimed to determine the characteristics, therapy, and outcomes of critically ill COVID-19 patients treated in the ICU. This was a multicentre retrospective study conducted in 12 hospitals in Indonesia from April 2020 to March 2021. All data regarding the characteristics, therapy, and outcomes of COVID-19 patients admitted to ICU were recorded and analysed. 1,502 patients were included in this study. Inpatient mortality occurred in 44.67% patients. The highest morbidity is attributed to stroke (83.4%). We found a significantly longer duration of mechanical ventilation use in non-survivors group (5.57 vs. 1.74 hours). Furthermore, the results of this study showed a significant difference in all type of treatment (excluding antifungal) between two groups. The mortality of COVID-19 patients in ICU is considerably high. Hypothyroidism and DMIІ patients showed a high serum asprosin, which linked with poor glycemic and lipid management. It is a biomarker for diabetes and thyroid issues.
