Study of the antibacterial effect of 5-(4-chlorophenyl)-1H-tetrazole and its oxime precursor against strains isolated from the hospital environment

نویسندگان

1 Organic Chemistry Laboratory (LCO), Faculty of Sciences Dhar El Mahraz–Sidi Mohammed Ben Abdellah University, Fez 30000, Morocco

2 Biotechnology Laboratory, Faculty of Sciences Dhar El Mahraz–Sidi Mohammed Ben Abdellah University, Fez 30000, Morocco

3 Biotechnology Laboratory, Faculty of Sciences Dhar El Mahraz–Sidi Mohammed Ben Abdellah University, Fez 30000, Morocco

4 Biotechnology Laboratory, Faculty of Sciences Dhar El Mahraz–Sidi Mohammed Ben Abdellah University, Fez 30000, Morocco

5 Biotechnology Laboratory, Faculty of Sciences Dhar El Mahraz–Sidi Mohammed Ben Abdellah University, Fez 30000, Morocco

doi
10.26655/jmchemsci.2018.6.5
چکیده

The compounds used in this study, TET and OXM, were tested in vitro for their antibacterial activities against isolated strains from the hospital environment (S. aureus H, E. coli H and K. pneumoniae H) and reference strains (S. aureus A, E. coli A, B. subtilis A and P. aeruginosa A). The calculation of the MBC/minimum inhibitory concentration ratio of the products TET and OXM showed that the two products have a bactericidal effect on the strains tested.

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